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topnurse

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Study points to possible new therapy for hearing loss

Researchers have taken an important step toward what may become a new approach to restore the hearing loss. In a new study, out today in the European Journal of Neuroscience, scientists have been able to regrow the sensory hair cells found in the cochlea -- a part of the inner ear -- that converts sound vibrations into electrical signals and can be permanently lost due to age or noise damage.

Hearing impairment has long been accepted as a fact of life for the aging population -- an estimated 30 million Americans suffer from some degree of hearing loss. However, scientists have long observed that other animals -- namely birds, frogs, and fish -- have been shown to have the ability to regenerate lost sensory hair cells.

"It's funny, but mammals are the oddballs in the animal kingdom when it comes to cochlear regeneration," said Jingyuan Zhang, Ph.D., with the University of Rochester Department of Biology and a co-author of the study. "We're the only vertebrates that can't do it."

Research conducted in the lab of Patricia White, Ph.D., in 2012 identified a family of receptors -- called epidermal growth factor (EGF) -- responsible for activating support cells in the auditory organs of birds. When triggered, these cells proliferate and foster the generation of new sensory hair cells. She speculated that this signaling pathway could potentially be manipulated to produce a similar result in mammals. White is a research associate professor in the University of Rochester Medical Center (URMC) Del Monte Institute for Neuroscience and lead author of the current study.

"In mice, the cochlea expresses EGF receptors throughout the animal's life, but they apparently never drive regeneration of hair cells," said White. "Perhaps during mammalian evolution, there have been changes in the expression of intracellular regulators of EGF receptor family signaling. Those regulators could have altered the outcome of signaling, blocking regeneration. Our research is focused on finding a way switch the pathway temporarily, in order to promote both regeneration of hair cells and their integration with nerve cells, both of which are critical for hearing."

In the new study, which involved researchers from URMC and the Massachusetts Ear and Eye Infirmary, which is part of Harvard Medical School, the team tested the theory that signaling from the EGF family of receptors could play a role in cochlear regeneration in mammals. The researchers focused on a specific receptor called ERBB2 which is found in cochlear support cells.

The researchers investigated a number of different methods to activate the EGF signaling pathway. One set of experiments involved using a virus to target ERBB2 receptors. Another, involved mice genetically modified to overexpress an activated ERBB2. A third experiment involved testing two drugs, originally developed to stimulate stem cell activity in the eyes and pancreas, that are known activate ERBB2 signaling.

The researchers found that activating the ERBB2 pathway triggered a cascading series of cellular events by which cochlear support cells began to proliferate and start the process of activating other neighboring stem cells to become new sensory hair cells. Furthermore, it appears that this process not only could impact the regeneration of sensory hair cells, but also support their integration with nerve cells.

"The process of repairing hearing is a complex problem and requires a series of cellular events," said White. "You have to regenerate sensory hair cells and these cells have to function properly and connect with the necessary network of neurons. This research demonstrates a signaling pathway that can be activated by different methods and could represent a new approach to cochlear regeneration and, ultimately, restoration of hearing."

Story Source:

Materials provided by University of Rochester Medical CenterNote: Content may be edited for style and length.

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tammybarney

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Babies born by C-section are at greater risk of picking up superbugs and suffering from allergies, scientists fear

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Exposure to the right microbes has been linked to having fewer auto-immune diseases such as asthma and allergies, and there are fears babies delivered via C-section are missing out on them.


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2 Chronicles 7:14                

If my people, which are called by my name, shall humble themselves, and pray, and seek my face, and turn from their wicked ways; then will I hear from heaven, and will forgive their sin, and will heal their land.
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BobBarney

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Why drinking red wine is a GOOD thing: The seven reasons why your nightly tipple is a healthy choice - but how much is too much?

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If you're looking for a healthier tipple, it's been shown red wine is better for you. According to experts, reds come packed with plant compounds laden with health benefits.

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LOWinLA
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As the old saying goes, everything in moderation 
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BobBarney

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Scientists warn too much of 'superfood' oatmeal topping flaxseed 'could cause cyanide poisoning' 

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Flaxseed contains a naturally occurring compound that can produce cyanide gas as it degrades. Adults could end up ill if they consume just three teaspoons of it in one sitting.

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Buck

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Molecular biologists have identified dozens of compounds in leech saliva that can reduce inflammation, disinfect wounds, dilate blood vessels, and prevent clotting. Clinicians have made use of these substances to manage knee pain from osteoarthritis; drain large collections of blood, called hematomas; and treat patients recovering from tissue transplants and reconstructive surgeries.

In 2004, the Food and Drug Administration cleared leeches for medical use — along with flesh-eating maggots that gnaw on rotting wounds — for tricky surgical procedures, like reattaching a thumb or flap of skin.

“When you attach something, you have to connect arteries, veins, tendons — the whole bit,” says Marcia Barnes, a nursing professor at Cumberland University who’s worked in plastic surgery for more than 20 years.

Often, it takes time for blood to start flowing well through a surgically connected vein, after the procedure. The resulting fluid congestion can cause clogging, damaging the delicate, newly attached tissues.

“When we become concerned about the blood collecting in that area, we’ll jump to leech therapy,” Barnes says. “They do it so well.”

Hospitals that use leeches have strict guidelines for leech therapy. Nurses rarely place more than six leeches on a patient at a time. Once a leech has done its job, it’s dunked in a bleach solution and disposed of.

And those leeches don’t come from the wild, like some far-flung lake in Bulgaria. Pharmaceutical companies supply hospitals with leeches from special manufacturers that grow the animals for medical use.

At one of those facilities, a company called Biopharm, based in Wales, maturing leeches are cared for by Carl Peters-Bond, an aquaculture specialist who’s raised leeches for over two decades. He feeds newborns sheep’s blood and monitors their growth, moving them from tropical conditions to cooler tanks as they age.

The animals can be difficult to rear. Leeches fed the same meals grow to different sizes. They’ll breed one week and not the next. And a leech can’t be sent off to a hospital until its stomach is empty, so Peters-Bond puts his leeches on a fasting diet. He makes sure the hungry parasites don’t eat each other and oversees a daily swimming regiment.

“They need exercise,” he says. “Bit like us really. If we sit on the couch we’re not going to lose any weight. So we’ve got to keep them moving.”

He’s heard of people who use leech therapy outside of hospitals, but he’s largely skeptical of the practice. “Some of them are a bit weird,” he says. “There’s not enough evidence on quite a lot of it to say that they’re going to work.”

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ThePlainTruth

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[image]

Leeches latest health trend...

More men go to spa...
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BobBarney

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The jab has previously been labelled by its British developers as 'the most exciting' treatment yet for tackling obesity.  

A weight-loss jab developed by British scientists has helped overweight patients shed 10lbs in a month. Stock photo

Millions of people in the UK are obese – around a quarter of adults and almost a fifth of children, figures show.

Obesity and type 2 diabetes can lead to very serious and potentially life-threatening conditions such as cancer, stroke and heart disease.

Professor Tricia Tan, lead author of the study, said: 'There is a real need to find new medicines so we can improve and save the lives of many patients.

'Although this is a small study our new combination hormone treatment is promising and has shown significant improvements in patients' health in only four weeks.

https://www.dailymail.co.uk/health/article-7327101/Weight-loss-jab-dubbed-exciting-obesity-treatment-helps-patients-lose-10lbs-month.html

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BobBarney

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New artificial intelligence MRI scans could take just five minutes instead of 90

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Researchers from New York University found that rather than current MRI scans that require patients lie still for up to an hour-and-a-half, their project takes just five minutes, with AI 'filling in the gaps'.

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BobBarney

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End those snory, sleepless nights... with a throat lift! People who suffer from a severe sleep disorder to benefit from pioneering new throat procedure

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People who suffer from a severe sleep disorder that stops them from breathing at night are set to benefit from a radical new procedure that ‘remodels’ the inside of the throat

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Tamster

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How your daily prescription pills could be draining your body of vital vitamins (and what you can do about it!)

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Prescription medication can also deprive people of vital minerals and vitamins, leading to hair loss, fatigue, depression and loss of sex drive. Here we look at the drugs that can ‘drain’ your body...


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"Stand with anybody that stands RIGHT. Stand with him while he is right and PART with him when he goes wrong." --Abraham Lincoln
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Any people anywhere, being inclined and having the power, have the right to rise up, and shake off the existing government, and form a new one that suits them better. This is a most valuable - a most sacred right - a right, which we hope and believe, is to liberate the world.

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topnurse

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Gonorrhea is a smart bug. It has developed resistance to every class of antibiotic we have thrown at it. In the U.S., we are on our last line of options to treat gonorrhea — a combination of the antibiotics azithromycin and ceftriaxone.

Quote:
Originally Posted by BobBarney

Super gonorrhea threat — it's a public health crisis that is on the horizon

Super gonorrhea threat — it's a public health crisis that is on the horizon
© Getty Images

A British man has been diagnosed with what some are calling the world’s “worst-ever” case of gonorrhea – a strain that is reportedly resistant to all antibiotics normally used to treat the disease.

This report is a confirmation of one of our greatest fears — untreatable gonorrhea could be on the very near horizon at a time when rates of the infection and of STDs overall are at record highs in this country. When we see a case like this in the U.K., it’s not a question of if, but when we’ll see it in the U.S. And once it’s here, it could spread quickly.

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ThePlainTruth

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Could deafness be reversed? Scientists re-grow damaged hair cells that have been killed off by age or noise inside the ear





Yes, Tio2 is in all WHITE PAINT.... We use it at Tamco, it's not a good idea to brush your teeth with or or even eat it (and yes it is in foods too!)

Could your TOOTHPASTE give you type 2 diabetes? White coloring used in food, suncream and toiletries could lead to the condition, study finds

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Researchers at the University of Texas have discovered that crystallised particles of titanium dioxide, a commonly used white colouring, may lead to type 2 diabetes.

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BobBarney

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Polio is spread by fecal matter entering the body via the mouth. thats how it spreads. want to stop it? have people stop eating food with feces in it.

Polio makes comeback in Venezuela after decades

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BillB

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Turmeric, which gives many foods an almost neon glow, can now be found in everything from drinks, yogurts and bread to buns, biscuits and even popcorn.

Fancy a turmeric latte? How about a turmeric-infused bag of popcorn, washed down with a turmeric tea? And maybe later you can dab on a little turmeric face cream? Not too long ago, this golden spice was just another powder at the back of the cupboard

Undoubtedly, the surge in interest is at least partly due to news about the alleged health-giving benefits of the root, which in its raw form looks a bit like ginger, linking it to everything from aiding gut ailments and easing joint pain to helping stave off depression and even preventing cancer.

Whether or not the aromatic taste of turmeric appeals is one thing. But is eating it doing us any good? Here we examine the facts (and some myths) to help you decide if you need to get some in…

LESS PAINFUL JOINTS

Numerous trials have concluded that the spice – or rather, its active ingredient curcumin, which makes up around three per cent of the powdered spice – could help ease the pain of arthritis.

Most arthritis studies have used a concentrated extract of the spice containing at least 500mg curcumin, which would equate to over five and a half teaspoons of turmeric powder. But at these sort of levels it’s a promising treatment. In a small 2012 pilot study, a concentrated pill form of curcumin under the brand name BCM95 reduced joint pain and swelling in patients with active rheumatoid arthritis better than diclofenac, a nonsteroidal anti-inflammatory drug (NSAID).

Biocurcumax (£21.99 from bioturm.co.uk) supplies the BM95 form with 650mg in a daily dose of two capsules.

LOWER DIABETES RISK?

A study published in Diabetes Care in 2012, found that people with prediabetes who took curcumin for nine months had improved function of insulin-producing cells in the pancreas. About 240 people were involved in the study and, after nine months of treatment 16 per cent of subjects in the placebo group were diagnosed with type 2 diabetes, but none in the curcumin-treated group.

The results sound impressive but need replicating, ideally with lower dosages, as the amounts used in this study were in a concentrated curcumin supplement form – equating to 16 teaspoons of turmeric powder. It’s more easily achieved by taking three capsules daily of a 500mg supplement such as Opti-Turmeric (£18.95 for 50 capsules from health span.co.uk) – though the recommended daily dose is two.

A study published in Diabetes Care in 2012, found that people with prediabetes who took curcumin for nine months had improved function of insulin-producing cells in the pancreas

BALM FOR THE BOWELS

A handful of small clinical trials suggests that curcumin can help people with ulcerative colitis. A study in Clinical Gastroenterology and Hepatology in 2015 found that for people with mild to moderate ulcerative colitis taking the standard medication of mesalamine, the addition of a high-dose curcumin supplement (equivalent to 30-plus teaspoons of turmeric powder) helped half of them achieve remission after four weeks. None given a placebo benefited.

More trials are needed to confirm the findings.

CALM THE BLOOD PRESSURE 

Curcumin supplements may improve the ability of blood vessels to dilate and expand, which enables blood pressure to normalise during stress. In a 2012 Japanese study involving 32 post-menopausal women split into three groups, those who took high- dose curcumin supplements had the same improvement in artery flexibility as those who did aerobic exercise. A placebo group saw no improvement.

An Iranian study reported in Phytotherapy Research in 2013 also found a reduction in triglycerides in those taking 1g curcumin a day – about 11 teaspoons of turmeric powder or 2 x 500mg curcumin capsules. Elevated levels of triglycerides make the blood sticky and thick, increasing the risk of clots.

WHAT DOESN’T IT WORK FOR?    Read morehttp://www.dailymail.co.uk/health/article-5798885/Turmeric-touted-magic-bullet-joint-pain-eczema-depression.html#ixzz5HMnkQKCB

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BobBarney

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AI better at finding skin cancer than doctors

A computer was better than human dermatologists at detecting skin cancer in a study that pitted human against machine in the quest for better, faster diagnostics, researchers said
A computer was better than human dermatologists at detecting skin cancer in a study that pitted human against machine in the quest for better, faster diagnostics, researchers said (AFP Photo/JOE RAEDLE)
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Paris (AFP) - A computer was better than human dermatologists at detecting skin cancer in a study that pitted human against machine in the quest for better, faster diagnostics, researchers said Tuesday.

https://www.yahoo.com/news/ai-better-finding-skin-cancer-doctors-study-230756918.html

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BobBarney

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Challenging yourself, taking aspirin and drinking champagne: The six proven ways to prevent dementia according to science

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Anna Magee writes for Healthista during Dementia Action Week. Experts say an active mind and body, aspirin and alcohol may all help to stave off the brain decline common in older people.

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tammybarney

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The divided states of America: Major health study warns US is at breaking point as the wealthy coasts thrive and the poor south is crushed by drugs, heart disease, obesity and cancer 

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In 21 states in the US, people were more likely to meet an early death in 2016 than they were in 1990, according to the most comprehensive study of US health disparities to date.


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Tammy Barney

2 Chronicles 7:14                

If my people, which are called by my name, shall humble themselves, and pray, and seek my face, and turn from their wicked ways; then will I hear from heaven, and will forgive their sin, and will heal their land.
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BobBarney

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Scientists discover new organ spanning the ENTIRE human body that acts as a built-in 'shock absorber'

Humans have been studying the anatomy of our own bodies for thousands of years – but, to this day, scientists are still uncovering new secrets.

A team of researchers has identified what’s said to be a previously undiscovered organ, and may even be one of the largest in the body.

What was once thought to be dense, connective tissues running all throughout the body has now been found to be a network of fluid-filled compartments that may act as ‘shock absorbers.’

Not only could the finding reshape our understanding of the human body, but scientists say it could help to explain why cancer is more likely to spread when it invades certain areas.

Dubbed the ¿interstitium,¿ interconnected compartments act like a ¿highway of moving fluid¿ that sits beneath the top layer of the skin (as shown above), lines the digestive tract, lungs and urinary systems, and surrounds the arteries, veins, and the fascia between muscle

The NYU-led team says the newly discovered organ is found all over the body – but somehow, it hasn’t been identified until now.

http://www.dailymail.co.uk/sciencetech/article-5551189/Scientists-discover-new-organ-spanning-ENTIRE-human-body-acts-built-shock-absorber.html

 

Dubbed the ‘interstitium,’ interconnected compartments act like a ‘highway of moving fluid’ that sits beneath the top layer of the skin, lines the digestive tract, lungs and urinary systems, and surrounds the arteries, veins, and the fascia between muscle.

The human body contains huge amounts of fluid.

More than half of this is found within the cells, and another seventh inside the heart, blood vessels, lymph nodes, and lymph vessels. The rest is known as interstitial.

Now, researchers say the network that carries this interstitial fluid is its own distinct organ.

And, it may even be one of the largest organs in the body.

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BobBarney

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Will this be the end of coeliac disease? Breakthrough treatment vaccine could help tens of thousands suffering gluten intolerance

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A breakthrough vaccine, which is currently being trialled in Perth, claims it could help people with coeliac disease to eat gluten without getting ill. The vaccine could be on the market in two years.

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BobBarney

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A vaccine for prostate cancer? British scientists design a breakthrough drug which boosts the immune system's ability to track down and kill deadly cells as soon as they appear

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The research is at an early stage, but scientists from Queen’s University Belfast believe their findings could be used to vaccinate young men against getting prostate cancer.


7 Foods That Prevent Prostate Cancer

                                Prostate cancer is the second leading cause of cancer deaths in men. According to the American Cancer Society, one in six men will be diagnosed with prostate cancer during his lifetime, and the disease kills more than 32,000 Americans each year. Yet, hundreds of studies have shown that certain foods, such as tomatoes and fish, are powerful cancer-fighters. 

 

Improve the odds of avoiding prostate cancer by adding generous helpings of the following foods to your anti-cancer diet: 

 

[broccoli]

1. Cruciferous vegetables

A study from the Fred Hutchinson Cancer Research Center in Seattle found that men who ate three servings a week of cruciferous vegetables, which include cabbage and broccoli, lower their odds of developing prostate cancer by 41 percent. These veggies contain two powerful phytochemicals, glucosinolates and isothiocyanates, which are believed to neutralize cancer-causing substances. 

Another study reported in the Journal of Biological Chemistry found that a compound in cruciferous vegetables called indole-3-carbinol, is converted by the body into DIM, a substance which blocks male hormones and keeps prostate cancer cells from growing.

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EdithWatts

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Reply with quote  #22 

 

 

 

Are you taking too many vitamins? Americans pop them by the handful - but some supplements are linked to cancer, diarrhea and kidney stones

 

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More than half of Americans take at least one supplement on a regular basis, but they have no proven benefits for most healthy adults, and some carry serious risks, experts explain.

 

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tammybarney

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Half of Americans have cold sores and 12% have genital herpes - a huge drop since 2000, new CDC report reveals

New drug could treat cold sores better than anything else on the market, scientists discover, after trying to cure eye herpes

A new treatment could someday quickly clear up even the most aggressive herpes outbreaks, a new study reveals.

Scientists at the University of Illinois at Chicago discovered - quite by accident- a new treatment that effectively stopped infections of herpes 1, the same virus that causes cold sores, in the cornea.

Instead of attacking the virus itself, the medication keeps the virus from producing proteins that are key to the replication of herpes and the drug is advantageous because the virus may not become resistant to it. 

The new treatment showed promise for treating herpes 1 in other locations and the researchers are ‘optimistic’ that it may be effective for genital herpes and perhaps even a broad set of viruses.

A new drug could be a revolution in treating not only ocular but oral and genital herpes 


Read more: http://www.dailymail.co.uk/health/article-5392345/New-drug-treat-cold-sores-better-else.html#ixzz57B26nwo3

Both the typically oral and genital forms of herpes are common STDs that cause lesions which can leave people vulnerable to other infections, like HIV. New CDC data reveal that rates of herpes are finally falling


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Tammy Barney

2 Chronicles 7:14                

If my people, which are called by my name, shall humble themselves, and pray, and seek my face, and turn from their wicked ways; then will I hear from heaven, and will forgive their sin, and will heal their land.
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Callie
Reply with quote  #24 

Dentists may soon be able to trigger teeth REGROWTH by stimulating stems cells which can also fix cavities

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Teeth can already repair small problems on the outer layers of teeth. But two recent Kings College London studies show that treating the stem cells within the tooth pulp can trigger them to fix cavities


Wine destroys bacteria that causes cavities and gum disease, paving the way for new toothpastes and mouthwashes containing the key antioxidant

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Researchers from the Spanish National Research Council in Madrid found antioxidants in wine significantly prevent bacteria that cause plaque and cavities from sticking to gums.

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BobBarney

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Scientists discover strong link between diabetes and Alzheimer's: Drugs used to control glucose levels may halt progression of dementia

Fiber is more powerful than we thought: Scientists find whole grains could be pivotal to controlling blood sugar levels in type 2 diabetics

 

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New research by Rutgers University has found fiber plays a far more active role than ever recorded in nurturing the gut bacteria that control blood sugars and fats.

 

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tammybarney

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Blood pressure secret is unlocked: Hope for better drug treatments after major breakthrough by British experts 

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The discovery, by scientists at King's College London, could allow doctors to mimic the body's method of regulating blood pressure, such as by stimulating the nerves with enzymes.


__________________
Tammy Barney

2 Chronicles 7:14                

If my people, which are called by my name, shall humble themselves, and pray, and seek my face, and turn from their wicked ways; then will I hear from heaven, and will forgive their sin, and will heal their land.
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BobBarney

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Scientists REVERSE brain damage in girl, 2, who almost drowned in a pool using oxygen therapy

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BobBarney

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Breast cancer cells start spreading to other parts of the body long before a tumor is even detected

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Researchers from the Icahn School of Medicine, New York, found that even before cancer is diagnosed breakaway cancer cells head off to infiltrate other bodily organs.

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ThePlainTruth

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Statins may RAISE the chances of diabetes: Cholesterol-lowering pills increase the likelihood of the condition - but doctors say the benefits 'outweigh the risks'

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BobBarney

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